https://www.indeelabs.com/articles daily 0.75 2025-09-18 https://www.indeelabs.com/articles/sequential-multiplex-editing-with-hydropore-enables-universal-armored-car-t-therapies monthly 0.5 2025-09-18 https://images.squarespace-cdn.com/content/v1/6008862cd4535b44c9031c71/cb183da5-6c78-4761-b9c4-c000bd8d6ec5/fig+3.jpg Articles - Sequential Multiplex Editing with Hydropore Enables Universal Armored CAR-T Therapies - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/6008862cd4535b44c9031c71/2cbe4460-e490-449c-a8a2-a8fc5f5efb3d/fig+4.jpg Articles - Sequential Multiplex Editing with Hydropore Enables Universal Armored CAR-T Therapies - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/6008862cd4535b44c9031c71/2bfa5152-7df3-4466-9cc1-b7ce0c670750/fig+1.jpg Articles - Sequential Multiplex Editing with Hydropore Enables Universal Armored CAR-T Therapies - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/6008862cd4535b44c9031c71/40881d8d-0b7f-4e49-85c2-f869f91f43a9/1+.jpg Articles - Sequential Multiplex Editing with Hydropore Enables Universal Armored CAR-T Therapies - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.indeelabs.com/articles/microfluidic-vortex-shedding-enhances-genome-edited-chimeric-antigen-receptor-t-cell-function-sz8fp monthly 0.5 2023-11-06 https://images.squarespace-cdn.com/content/v1/6008862cd4535b44c9031c71/c1d96c4b-751e-44a4-bc14-879fc95bd575/hydroporated+cells.png Articles - Microfluidic Vortex Shedding Enhances Genome-Edited Chimeric Antigen Receptor T Cell Function - Make it stand out Figure 4. Hydroporated cells showed reduced AICD and improved motility when compared with nucleofected cells. Activation-induced cell death and cell motility upon target cell engagement for hydroporated cells (red) and nucleofected cells (green) across 5 donors. Showing % of AICD at different ratios of effector cells to target cells at either (a) 1E:1T, (b) 1E:2+T, (c) 1E:1+T and (d) summary E:T ratios. Motility during synapse at (e) 1E:1T, (f) 1E:2T, (g) 1E:2T, and (h) motility summary for different targets and E:T ratios. https://images.squarespace-cdn.com/content/v1/6008862cd4535b44c9031c71/a5210622-0d9f-4bfc-bc11-b21b5b383db4/figure+5.png Articles - Microfluidic Vortex Shedding Enhances Genome-Edited Chimeric Antigen Receptor T Cell Function - Make it stand out Figure 5. Hydroporated cells showed reduced perturbation of cytokine profiles. Volcano plot depicting resting T cell cytokine secretion fold changes and P values for supernatants collected 24 hours after processing (a) hydroporated TCR knockout, (b) nucleofected TCR knockout, c) hydroporated AAV CAR-T knock-in and (d) nucleofected AAV CAR-T knock-in. (e) summary of up/down regulated proteins relative to the NTC. https://images.squarespace-cdn.com/content/v1/6008862cd4535b44c9031c71/1a69e070-1a95-4017-acc7-1ef4f7e37b62/timing+assay.png Articles - Microfluidic Vortex Shedding Enhances Genome-Edited Chimeric Antigen Receptor T Cell Function - Make it stand out Figure 2. Image showing cells within the TIMING assay nanowells. CAR-T effector cells (green) and NALM6 target cells (orange) in TIMING assay nanowells at various effector-to-target cell ratios (E:T) at t=0. https://images.squarespace-cdn.com/content/v1/6008862cd4535b44c9031c71/1bf8e02a-89a2-4cc1-a32f-fe8d1196759f/1.png Articles - Microfluidic Vortex Shedding Enhances Genome-Edited Chimeric Antigen Receptor T Cell Function - Make it stand out Figure 1. CAR-T cells transfected via hydroporation showed improved viability, proliferation, and EGFPR+ cells. (a) viability of cells vs days post-transfection, (b) number of viable cells vs days post-transfection, and (c) number of EGFR+ cells when transfected by either hydroporation or nucleofection. (d) cytotoxicity at different effector-to-target cell ratios. https://images.squarespace-cdn.com/content/v1/6008862cd4535b44c9031c71/e97dd15c-edd7-4703-bfde-79a77364ada6/figure+6.png Articles - Microfluidic Vortex Shedding Enhances Genome-Edited Chimeric Antigen Receptor T Cell Function - Make it stand out Figure 6. Hydroporated cells showed a significant change in cytokine profiles when directly compared to nucleofected cells. Volcano plot depicting resting T cell cytokine secretion fold changes and P values for supernatants collected at 24 hours (a) nucleofected cells vs hydroporated cells in NTC, (b) nucleofected cells vs hydroporated cells in TRC KO treated cells and c) nucleofected cells vs hydroporated cells in TRC KI treated cells. (d) summary of up/down regulated proteins relative to hydroporated cells. https://images.squarespace-cdn.com/content/v1/6008862cd4535b44c9031c71/4bd35393-7d3e-4619-82f0-cdb21e08369c/figure+7.png Articles - Microfluidic Vortex Shedding Enhances Genome-Edited Chimeric Antigen Receptor T Cell Function - Make it stand out Figure 7. Hydroporated CAR-T cells showed a significant difference in cytokine profiles compared to nucleofected CAR-T cells. Volcano plot depicting resting T cell cytokine secretion fold changes and P values for supernatants collected at 24 hours (a) nucleofected vs hydroporated CAR-T cells at a 1:1 E:T ratio, (b nucleofected vs hydroporated CAR-T cells at a 1:2 E:T ratio, (c) nucleofected vs hydroporated CAR-T cells at a 1:4 E:T ratio (d) nucleofected vs hydroporated CAR-T cells at a 1:8 E:T ratio. (e) heat map showing significant differences in up and down-related protein changes in hydroporated CAR-T cells vs nucleofected CAR-T cells. https://images.squarespace-cdn.com/content/v1/6008862cd4535b44c9031c71/ee54402d-84d7-4d6b-adba-cf1336493d9a/car-t+cells.png Articles - Microfluidic Vortex Shedding Enhances Genome-Edited Chimeric Antigen Receptor T Cell Function - Make it stand out Figure 3. CAR-T cells modified through hydroporation showed no significant differences in tSeek, tContact and tTarDeath values when compared to nucleofected cells. Time-based measurements of T cell target engagement of hydroporated cells (red) and nucleofected cells (green), including (a) time to synapse formation, (b) duration of synapse formation, (c) time to target cell death, (d) percentage of synapse formation, (e) percentage of spontaneous T cell death, and (f) percentage of target cell lysis with one or more target cells. https://www.indeelabs.com/articles/automating-primary-human-t-cell-culture monthly 0.5 2023-07-10 https://images.squarespace-cdn.com/content/v1/6008862cd4535b44c9031c71/db41e81d-1bcb-47d0-89b6-4b078e0df463/Screen+Shot+2023-07-10+at+10.03.29+AM.png Articles - Automating Primary Human T cell Culture - Make it stand out Figure 1 Overview of the automated cell culture work cell and software platform. https://images.squarespace-cdn.com/content/v1/6008862cd4535b44c9031c71/cab41b28-c9f5-4db9-8d60-d3ec54a87281/Yellow+and+Black+Text+Safety+Yard+Sign.png Articles - Automating Primary Human T cell Culture - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/6008862cd4535b44c9031c71/16191062-8a39-492c-aacd-6238c36c92b7/Screen+Shot+2023-06-28+at+2.39.18+PM.png Articles - Automating Primary Human T cell Culture - Make it stand out Figure 2 Results comparing automated and manual T cell culture and passaging. https://www.indeelabs.com/articles/cyclic-peptide-screening monthly 0.5 2023-06-29 https://images.squarespace-cdn.com/content/v1/6008862cd4535b44c9031c71/2d85df41-7b32-4cd9-ad67-4cc55e4105b1/Screen+Shot+2023-05-24+at+4.44.23+PM.png Articles - Screening Cyclic Peptides With Hydropore - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/6008862cd4535b44c9031c71/9d5d000e-71dc-4cae-b968-9dd1f7ad0c8e/Picture1.png Articles - Screening Cyclic Peptides With Hydropore - Make it stand out Figure 1 A short window of cell permeability after Hydropore-processing. https://images.squarespace-cdn.com/content/v1/6008862cd4535b44c9031c71/e320f973-5573-4bb2-9536-51ec220daa19/Picture3.png Articles - Screening Cyclic Peptides With Hydropore - Make it stand out Figure 3 Screening of additional peptides. https://images.squarespace-cdn.com/content/v1/6008862cd4535b44c9031c71/e94fe5e7-7a38-42a2-a286-ac46262129f9/Picture2.png Articles - Screening Cyclic Peptides With Hydropore - Make it stand out Figure 2 Overview of the DµVS system. https://www.indeelabs.com/articles/introducing-hydropore-for-cell-biology-and-cell-therapy-research monthly 0.5 2023-05-30 https://images.squarespace-cdn.com/content/v1/6008862cd4535b44c9031c71/1623105231946-BK566SASSGVLCF7S8E3P/HERO+ANGLE+%281%29.jpg Articles - Introducing Hydropore™ for Cell Biology & Cell Therapy Research - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/6008862cd4535b44c9031c71/1623253811293-QMSLNWBJ7YQRS3S3DRAE/Figure-3-Transfection-Steps.png Articles - Introducing Hydropore™ for Cell Biology & Cell Therapy Research - Make it stand out Figure 3 Hydropore™ transfection protocol https://images.squarespace-cdn.com/content/v1/6008862cd4535b44c9031c71/1623109743916-A0Y37Z6PHKOA4KHUPVVO/Figures-Large-Whitepaper.png Articles - Introducing Hydropore™ for Cell Biology & Cell Therapy Research - Make it stand out Table 1 Comparison of Hydropore™ to an RUO electroporation system. 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