Publications & Patents
Nature Scientific Reports (2025) Scalable intracellular delivery via microfluidic vortex shedding enhances the function of chimeric antigen receptor T-cells
AIChE Bioengineering & Translational Medicine (2023) A high-throughput microfluidic mechanoporation platform to enable intracellular delivery of cyclic peptides in cell-based assays
Nature Scientific Reports (2021) Numerical optimization of microfluidic vortex shedding for genome editing T cells with Cas9
Nature Scientific Reports (2019) Intracellular delivery of mRNA to human primary T cells with microfluidic vortex shedding
Patent WO2019084624A1 Intracellular delivery and method therefore
Patent WO2016109864A1 A method for mechanical and hydrodynamic microfluidic transfection and apparatus therefor
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Hydropore™ is developed in a regulatory-ready manner and currently available for Research Use Only. A clinical system will be regulated as a tool for biologics manufacturing. Both systems are developed in an ISO 13485-compliant manner and all materials in the flow path are medical-grade or USP Class VI implantable-grade. Hydropore™ systems for high-throughput pooled screening of small volumes.

